Macroporous resin XAD-4 was used as adsorbent to remove polyethylene glycol (PEG) from aqueous solution by static adsorption method. The effects of initial pH value, contact time, adsorbent dosage and temperature on its adsorption performances were examined. The results showed that the initial pH value had little effect on adsorption properties. The removal rate of PEG could reach 89% and equilibrium adsorption capacity was up to 59.95 mg/g when XAD-4 dosage was 0.3 g/L. PEG was loaded on XAD-4 resin with an uniform distribution. The isotherm data fitted well with Langmuir, Dubinin-Radushkevich and Sips models. The adsorption process was exothermic and spontaneous. The kinetic adsorption data fitted well with the pseudo-second-order model.