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Synthesis of Phytosterol Esters Catalyzed by Immobilized Lipase in Solvent-free System

  • ZHOU Hai-yan JIANG Zhen-hua REN Li-wei YU Min ZHOU Hua WEI Ping
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  • College of Pharmacy and Life Science,Nanjing University of Technology College of Pharmacy and Life Science,Nanjing University of Technology College of Pharmacy and Life Science,Nanjing University of Technology College of Pharmacy and Life Science,Nanjing University of Technology College of Pharmacy and Life Science,Nanjing University of Technology College of Life Science and Pharmacy, Nanjing University of Technolog

Received date: 2015-08-19

  Revised date: 2016-02-01

  Online published: 2017-04-28

Abstract

The aim of this work is to synthesize lauric acid phytosterol esters by lipase in solvent-free system. The lipase was immobilized on macroporous resin NKA, with addition of dextran. The reaction conditions were optimized. The results showed that under the optimized conditions of a molar ratio of lauric acid to phytosterol of 6:1, 7.5% dextra of molecular weight 10 kDa and the reaction temperature of 60℃ in solvent-free system, the esterification rate reached 96.2% after 12 h. The reaction time of the synthess of phytosterol esters decrease 4 h comparing with the immobilized lipase on a macroporous resin.

Cite this article

ZHOU Hai-yan JIANG Zhen-hua REN Li-wei YU Min ZHOU Hua WEI Ping . Synthesis of Phytosterol Esters Catalyzed by Immobilized Lipase in Solvent-free System[J]. The Chinese Journal of Process Engineering, 2016 , 16(3) : 500 -504 . DOI: 10.12034/j.issn.1009-606X.215298

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