Spiral insert is fixed in a heat exchanger tube for formation of spiral fluid flow. The effects of particle diameter, particle concentration, spiral structure parameters and temperature difference on the heat transfer enhancement and anti-fouling performance were examined by experiments. The results show that in the experimental ranges, comparing the values of heat transfer coefficient in different cases, the spiral fluidization is 15%~20% higher than that of the spiral flow, the particles with the diameter of 5 mm 5.4% higher than that of 3 mm particles, the high particle concentration of 15%(j) 15.3% higher than that of 5%(j), the spiral outer diameter of 30 mm 7.7% higher than that of 20 mm, and the helical pitch of 20 mm 11.1% higher than that of 60 mm. With continuous operation, the decline of heat transfer coefficient of the inner tube spiral fluidization is much less than that of the spiral flow, indicating good anti-fouling effect of the spiral fluidization. The heat transfer enhancement and anti-fouling of spiral fluidization are less affected by the change of temperature difference.