Co-gasification reactivity of distillery residue and coal char with CO2 was studied by a fixed bed reactor. The pore structure, surface elemental composition and ash mineral composition of the experimental samples were investigated by scanning electron microscopy analysis methods, X-ray spectroscopy and X-ray diffraction. The results showed that the co-gasification reactivity of distillery residue and coal char with CO2 have significant synergies, and except CO2, the main production of this reactivity is CO, H2 and CH4. The highest concentration is produced of the three gases under the blending ratio of the distillery residue of 80%. The gasification temperature and the blending ratio of distillery residue are the major factors which affect the co-gasification reactivity. At the same blending ratio of distillery residue, the co-gasification reactivity increased with increasing temperature within a temperature range of 900?1100℃. At the same temperature, the co-gasification reaction activity increased with increasing of the blending ratio of distillery residue at the range of 20%?80%. Distillery residue contains volatile content as high as 69.47%, inducing a large amount of pore structure during gasification. The induced pore, the potassium and calcium contained in the distillery residue and coal char, are the main factors for improving the co-gasification reactivity.