The Fe-loaded activated carbon was prepared by liquid-phase chemical reduction procedure. The activated carbon, Fe-loaded activated before and after adsorption uranium ion were analyzed, its absorption property to uranium ion was studied. The results showed that Fe was embedded loosely as spheres in the pores of activated carbon which had a specific surface area of 10.3 m2/g, pore size of 0.0245 cm3/g and pore diameter of 10.5 nm. Some erosion and new crystals on iron surface were detected after adsorption uranium ion, contributing a rise in specific surface area of 16.7 m2/g, pore size of 0.0955 cm3/g and pore diameter of 17.9 nm. Redox, together with adsorption and precipitate, dominant the uranium ion removal efficiency. The maximum removal rate was 99% with mass ratio of FeSO4?7H2O to activated carbon of 1.25:1, Fe-AC concentration of 0.6 mg/mL , reaction time of 60 min, and pH value of 5.00. The uranium ion adsorption by Fe-loaded activated carbon matched Langmuir (R2=0.943) and Freundich (R2=0.992) models. The adsorption reaction could be described by a pseudo-second order kinetics equation (R2=0.999), and diffusion rate agreed with the membrane diffusion.