The leaching process of Fe, V and Ti from vanadium-bearing titanomagnetite pre-reduced by HCl was investigated, concerning the effect of variation factors on the leaching rate, and the phase-analysis of the leaching residue herein. The results showed under the optimal conditions, with initial concentration of HCl of 20%(?), mass ratio of liquid to solid of 4:1, leaching temperature of 110℃ and leaching time of 4 h, the leaching rate of Fe, V and Ti were 91.8%, 95.0%, and 0.3%, respectively. In the leaching process, Ti was firstly dissolved and subsequent hydrolysis-precipitation. The HCl leaching solution can be used for recovering iron and vanadium extraction in the subsequent process. The decomposition rate of TiO2 of HCl leaching residue by H2SO4 was reached up to 98.2%, deduced the HCl leaching residue can be used as raw materials for production of titanium white by sulfuric acid process.