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Reaction & Separation

Chromatographic Separation of Sialyllactose and Lactose in Bovine Coloctrum

  • Ming LI Jiachun ZHOU Zhen QIN Qiming CHEN Yongjun QIU Liming ZHAO
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  • State Key Laboratory of Bioreactor Engineering, R&D Center of Separation and Extraction Technology in Fermentation Industry, School of Biotechnology, East China University of Science and Technology, Shanghai 200237, China

Received date: 2017-03-13

  Revised date: 2017-04-13

  Online published: 2017-06-14

Abstract

Electrodialysis (ED) and nanofiltration (NF) were adopted to separate monovalent and divalent ions (Na+/Mg2+, Cl-/SO42-). The results showed that DL2540 had a better separation efficiency for the rejection of divalent ions than NF270. The rejection of Mg2+ and SO42- were 98.1% and 80.5%, respectively. For ED, the separation factors were 2.5 and 40.0. The separation performance of Cl-/SO42- was better than that of Na+/Mg2+, the separation factors were 18.4 and 2.9 under 90% recover rate of Na+. Both methods had good separation effects of monovalent and divalent ions. ED could also realize ions concentration, while NF could not.

Cite this article

Ming LI Jiachun ZHOU Zhen QIN Qiming CHEN Yongjun QIU Liming ZHAO . Chromatographic Separation of Sialyllactose and Lactose in Bovine Coloctrum[J]. The Chinese Journal of Process Engineering, 2017 , 17(3) : 506 -511 . DOI: 10.12034/j.issn.1009-606X.217174

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