An effective high temperature denitration catalyst hasn’t been proposed for gas turbine flue gas condition. Therefore, Ce?Fe/ZSM-5 catalyst was prepared to be used in denitration for gas turbine flue gas by impregnation method with ZSM-5 sieved as the carrier, Fe as the active component and Ce as the active additive. Based on the gas turbine flue gas condition, the physical and chemical properties such as denitrification performance, surface acidity and redox ability of the catalyst were systematically studied to research structure-activity relationship between catalyst structure and denitration effect. The results showed that when the Fe load was 4wt%, the NOx conversion rate of Fe/ZSM-5 catalyst was 77.11% at 550℃. The high temperature denitrification effect of Ce?Fe/ZSM-5 catalyst was significantly improved after Ce doping. When the Ce load was 1wt%, the NOx conversion rate remained at 95.92% at 550℃, the catalyst had excellent medium-high temperature catalytic activity, which was 18.81% higher than that of Fe4/ZSM-5. Moreover, the increase of oxygen content and NO2 concentration can improve the selective catalytic reduction (SCR) performance of the catalyst. The hydrothermal aging test showed that the catalyst had good hydrothermal stability. After aging at 10vol% H2O, 600℃ and 10vol% H2O, 800℃, the NOx conversion rate of catalyst was maintained about 90% in the range of 450?550℃. Characterization results indicated that proper cerium doping can promote the dispersion of iron oxides, enhance the content and strength of Lewis acid site, and increase the proportion of absorbed oxygen, the synergistic effect between Ce and Fe also improved the redox ability of catalyst at high temperature, these might be the reason for the better high temperature catalytic activity.