In this work, the numerical simulation model of the hexagonal tube with different parameter dimples has been established considering thermal-hydraulic performance. The effect of dimple types, dimple depth, and dimple diameter on the flow field characteristics, and heat transfer characteristics of dimple tubes were discussed under Reynolds numbers between 5000 and 40000. Skewness and kurtosis of dimpled tube wall surface were calculated by discrete method, and then the thermal-hydraulic performance of dimpled tube was analyzed based on the influence of dimple parameters on skewness and kurtosis. The results showed that the dimpled tube had a better thermal-hydraulic performance due to the recirculation flows and flow separation was a significant increase, and the effect of pit dimple was better than that of bulge dimple. In addition, the influence of different dimple types was that the less the skewness, the better the thermal-hydraulic performance of the heat transfer tube. However, for the pit dimple tube, the larger skewness and the smaller the kurtosis was, the better comprehensive performance of the thermal-hydraulic got. With the increase of the pit dimple depth and diameter, the skewness gradually increased, while the kurtosis value gradually decreased.