The two-phase flow of porous particles widely exists in industrial processes. However, the internal structure of most porous particles is heterogeneous, which has been homogenized in previous studies and may affect the interaction between the particle and the fluid. Therefore, the volume-average macroscopic control equation based on the intrinsic phase average velocity was used to describe the fluid flow inside and outside the porous particles. Then, an improved lattice Boltzmann method (LBM) was used to solve the macroscopic control equation. Two-dimensional fluid flow around and through a heterogeneous porous particle was simulated numerically. By introducing difficult-to-permeable regions to adjust the internal porosity of porous particle, the effect of heterogeneity on the force of particle and evolution of flow field was simulated. The results showed that the heterogeneous structure could induce the lift force of the particle and realize the longitudinal mass transfer inside the particle compared to the homogeneous porous particle. Moreover, both the lift force and the mass transfer strength increased with the increase of the hard-to-penetrate area and Da number due to the asymmetric interaction between the particle and the fluid, but showed a peak value with Da number increasing to sufficiently large, mainly because of the effect of the internal structure diminished as the great quantity of fluids through the particle. On account of the lift force and mass transfer in the longitudinal, the presence of the hard-to-penetrate area also generated the wake vortex behind the particle to no longer be symmetrically distributed at a lower Re number, and to fall off at the Re number around 38, which enhanced the intensity of the disturbance of the flow field. In general, the existence of heterogeneous structure inside particle has an important influence on the force of the particle-fluid system and the evolution of the flow field, which is worth considering in future research.