Conventional copper smelting technology combines two steps of smelting and converting, with oxygen-enriched smelting as a typical representative. Intermittent operations would inevitably cause common issues such as long operation procedures and low-level sulfur dioxide pollution. Therefore, development of short-process for copper smelting technology is particularly necessary. Direct to blister copper smelting technology was carried out in a single furnace. It has the advantages of short process, good environmental benefits, and low investment cost, which is in line with the development direction of modern short-process smelting technology. The high-grade copper concentrate was used as raw ore for direct to blister copper smelting in present, and the method of theoretical calculations combined with experiments in lab-scale was adopted to investigate the phase transformation, blister copper yield, and copper content in the slag during the smelting process. Theoretical calculations indicated that the spinel phase in the melt can be avoided by adding CaO, as the ratio of iron to silicon was controlled to be 0.6 in the raw material. The corresponding chemically dissolved copper content in the slag at 1300℃ was approximately 8.6wt%. The effects of the amount of injected oxygen and settling time on the weight of blister copper and slag properties was discussed. For 80 g raw material, the oxygen-enriched air (50vol% O2) with a rate of 0.4 L/min was injected for 70 min, and then settling for 2 h. The experimental results indicated that the blister copper with a recovery rate of 82.12% could be obtained from a high-grade copper concentrate containing 45.94% Cu via direct to blister copper smelting at 1300℃. SEM-EDS analysis method was used to investigate the microstructure of the slag, which indicated that a large amount of spinel phase existed in the slag, hindering the sedimentation of copper particle. The copper in the form of mechanical entrainment was observed as a result.