The purpose of this work is to explore the flow of power-law fluid in Kenics static mixer. The flow was affected by the element shearing action of Kenics static mixer. Discovery HR-2 rheometer was used to measure the consistency coefficient K and rheological index n of the carboxymethyl cellulose solution at 0.5wt%, 0.7wt% and 0.9wt%. The parameter of power-law fluid was provided for the numerical simulation. The computational fluid dynamics software Fluent was used to simulate the computational domain. The flow resistance and shear-thinning characteristic in the Kenics static mixer were experimentally measured and numerically simulated in the conditions of the element aspect ratio Ar=1.0~2.0 and the flow rate 50×10-6~450×10-6 m3/s. It was showed that the resistance coefficient of the twisted blade with Ar=2.0 was 66.6% lower and the viscosity was 9.0% higher than that with Ar=1.0. The flow research showed that the internal-flow vortex, the detour-flow vortex and the near-wall vortices were induced by twist blade. The formation and dissipation of near-wall vortices played a good role in drag reduction because the internal vorticity and shear stress were increased and the viscosity of carboxymethyl cellulose solution was effectively reduced. The longitudinal vortices enhanced the shear effect of fluid flow in the static mixer. Affected by the vortices, the highest velocity was at 45° of circumferential direction in the local flow field of the element. The highest vorticity, shear stress and the lowest viscosity were at 30° of circumferential direction. The velocity was the highest at 0.4 times radius and the viscosity was highest at 0.7 times radius. The secondary flow velocity and shear stress were improved effectively by Kenics static mixer, and the viscosity of power-law was reduced. The flow resistance coefficient was effectively reduced with the flow velocity increasing, the power-law fluid concentrations reducing and the element aspect ratio reducing. The study about flow characteristics of a power-law fluid in Kenics static mixer provided the basic data for optimizing structure design.