Circulating jet mixing tank (CJT) as a process intensification can improve the turbulent mixing and reaction selectivity of flowing working medium. In order to further improve its industrial application value, the heat transfer capacity of the flow field inside the CJT was analyzed and the number of jet layers was optimized. Under the condition of constant wall temperature, the SST k-ω model was used to analyze the flow heat transfer performance of the flow field in the non-steady state calculation. The heat transfer uniformity of the wall and the heat transfer characteristics in the flow field was studied at Re= 3260~16 303 and the number of jet layers M=5~9. The variation coefficient Ch of convective heat transfer coefficient decreased and the uniformity of wall heat transfer increased by 2.8%~19.3% with the increasing Re for M=9. The field-synergy between flow field and temperature field increased with the increase of Re and the synergy angle at Re=16 303 is 75.5o, which is 0.5° less than that at Re=3260. The Ch decreased and the heat transfer uniformity increased by 2.7%~16.3% with the increasing M for Re=9782. The field-synergy between velocity vector and temperature gradient decreased with the increasing M. Compared with synergy at M=5, the global synergy decreased by 6.1% at M=9. When M=7, the field-synergy angles in the central mixing region and the jet mixing region were between 73° and 74°, and the heat transfer capacity between the two regions was well matched. The synergy of central mixing region was better than that of jet mixing region for M<7, and the situation was opposite when M>7. The influence of Re and M on the heat absorption and transfer performance of the CJT was studied. It was found that the change of Re had more influence on the heat absorption of the CJT with respect to M.