As a key equipment in the cement production process, the combustion of gas-phase pulverized coal particles and the sintering reaction of solid-phase cement are carried out at the same time, which has a decisive impact on the generation of cement clinker products and the quality of products. However, due to the large difference in reaction rate and flow rate between the two processes, most of the existing simulations are limited to the study of a single solid-phase sintering or gas-phase pulverized coal combustion reaction process, and the interaction between the two processes is rarely discussed. In view of this shortcoming, an innovative gas-solid phase coupling simulation method was proposed, which divided the kiln area into three-dimensional gas-phase pulverized coal combustion zone and one-dimensional solid-phase cement sintering zone, which were simulated independently, and the close coupling between the two processes was realized through iterative calculation. The coupled simulation method effectively overcame the simulation challenges caused by the significant difference in flow velocity between the gas phase and the solid phase, and can more comprehensively reveal the interaction mechanism of fluid flow, heat transfer and chemical reaction in the kiln, providing a multi-scale coupled simulation method for the complex system of rotary kiln. The coupled simulation results showed that compared with the traditional single one-dimensional or three-dimensional simulation, this method can significantly improve the simulation accuracy, and the simulation results were highly consistent with the actual clinker output data of the plant. It can effectively guide the optimal design and operation process of rotary kiln, so as to improve the quality of clinker products, and provide an accurate and efficient simulation method for the simulation of cement rotary kiln.