设计加工了新型膜微反应器，分析了该设备对渗透汽化-反应耦合过程的强化作用. 以酯化反应为模型反应，在催化膜微反应器中，考察了有无渗透汽化作用下催化剂负载量和温度对酯化反应性能的影响. 结果表明，在反应停留时间60 min、温度65℃的条件下引入渗透汽化作用，转化率由13.6%提高至54.0%. 由于微反应系统的比表面积大且扩散距离短，过程微型化有利于副产物水的脱除，能强化膜分离与反应耦合过程. 在催化剂含量15%(w)、反应停留时间60 min、温度65℃的条件下，催化膜微反应器和常规尺寸催化膜反应器内的酯化反应转化率分别为54.0%和29.3%. 微反应设备中无需机械搅拌，对催化膜有保护作用.

A new type of membrane microreactor was designed and set up. The intensification of miniaturization for the coupling process of pervaporation and reaction was investigated. The esterification reaction was chosen as a model reaction. The influences of the content of catalyst and temperature on the reaction were examined in the membrane microreactor with and without pervaporation. The results showed that conversion rate rose from 13.6% to 54% with pervaporation under the conditions of 65℃ and residence time of 60 min. The large specific surface area and short diffusion distance of the membrane microreactor could promote the removal of water and intensify the coupling process of pervaporation and reaction. The conversion rate of esterification was 54.0% in the membrane microreactor and 29.3% in the conventional macro-scale membrane reactor under the conditions of 65℃, residence time 60 min and content of Zr(SO4)2 15%(w). In addition, the deactivation of catalyst could be effectively reduced in the membrane microreactor. Its repeatable utilization was improved.