中药制造业属于高能耗、高物耗(特别是水资源)、以热加工为主的过程工业。“双碳”目标下，中药制药流程的精制、浓缩、挥发油富集、制药工艺用水及注射剂安全保障、溶媒回收与废水处理等工序都面临严重的挑战。膜科技具有重大国家科技战略需求，是我国中药制药工业亟需推广的高新技术，多种膜过程的集成，几乎可与中药制药流程的各主要工序兼容。本工作提出面向中药绿色制造过程的特种膜系列概念，并就“双碳”目标下，采用中药特种“膜一体化”绿色制造技术，再造中药制药流程的有关科学技术问题开展讨论，其中涉及基于本课题组提出的中药“溶液环境”特征参数监控技术的浓缩能耗计算模式，以玉屏风散为模型药物，所获取的膜(反渗透、膜蒸馏)浓缩与蒸发浓缩的能量效率对比结果。提出了中药制药流程“全生命周期碳中和”的概念；以膜科技为核心的分离技术集成是实现中药工业生态园的重要途径。
The pharmaceutical process of traditional Chinese medicine is an energy-material intensive process, particularly with the requirement of large input of water resource and heat source. Under carbon peaking and carbon neutrality policy, the pharmaceutical industry of traditional Chinese medicine involving processes such as refinement, concentration, enrichment of aromatic compounds, solvent recovery, etc., facing unprecedented challenges. As the nation's strategic emerging technology, membrane technology can offer great potential in the manufacturing of traditional Chinese medicine. The integrated process of membrane technologies shows decent competency with the existing manufacturing procedures and steps for traditional Chinese medicine. This review intends to introduce the concept and categories of different specialized membranes particularly fabricated for the application in traditional Chinese medicine green manufacturing for various purposes. This work also reviews the potential, challenges and scientific problems regarding the reengineering of traditional Chinese medicine manufacturing process using integrated membrane processes under the carbon peaking and carbon neutrality policy. Particularly, an algorithm is developed to estimate energy consumption for membrane concentration technology using the key characteristics of the herbal extract solution, which can facilitate the energy comparison between conventional thermal evaporation and the integrated processes of both thermal and membrane concentration technology. This can be used for the process design and optimization of the pharmaceutical manufacturing of traditional Chinese medicine with minimum energy input. The concept of carbon neutral life cycle for traditional Chinese medicine manufacturing is introduced. This work also outlined the perspectives of integrated membrane processes in the eco-industrial park of traditional Chinese medicine manufacturing.
