浮选作为分选低品位矿石的有效手段之一，具有对细粒矿石分选效果明显、分选效率高等优点。为了取得更好的浮选分离效果，选用合理且绿色高效的抑制剂至关重要。作为一种新型有机抑制剂，凭借自身良好理化性质、绿色环保和易于制备等优点，壳聚糖被广泛应用于矿物浮选，并且多种壳聚糖衍生物同样具有优良的抑制性能。本工作综述了近几年来壳聚糖及其衍生物在多种矿物浮选试验中的研究进展，首先重点介绍了壳聚糖及多种新型衍生物作为抑制剂在矿物表面的主要吸附方式，其次总结了它们的抑制机理和影响抑制效果的主要因素，最后对壳聚糖衍及其衍生物抑制剂的未来研究方向进行探讨及展望。尽管壳聚糖及其衍生物抑制剂的相关研究日益成熟，但针对其产生抑制的主要机理研究仍然不够细致。随着各项检测手段的进步，如何在提高抑制效果的同时进一步明确产生抑制的相关基团及主要机理，将是未来壳聚糖衍生物抑制剂研究的一大重点。

As one of the most effective methods for low-grade ore separation, flotation has the advantages of obvious sorting effect on fine-grained ores and high separation efficiency. It is crucial to use reasonable and eco-friendly depressants in order to improve the flotation separation effect. As a new type of organic depressant, chitosan is widely used in mineral flotation due to its outstanding physical and chemical properties, environmental protection and easy preparation. Many chitosan derivatives also have excellent depression capabilities. In this work, the research progress of chitosan and its derivatives in flotation experiments of various minerals in recent years is reviewed. Firstly, the main adsorption methods of chitosan and its various novel derivatives as flotation depressants on mineral surfaces are introduced. Then, the depression mechanism and the main factors affecting the depression effect are summarized. Discussion and potential future research directions of chitosan derivatives depressants are also included. Although the research on chitosan and its derivative depressants is becoming more and more mature, the main depression mechanism is still not detailed enough. With the advancement of various detection methods, how to improve the depression effect and further clarify the related groups and main depression mechanisms will be a major focus of future research on chitosan derivatives depressants.